Category Archives: Uncategorized

American Exceptionalism: We are an Outlier

As several members of our Supreme Court looks to apply the “original intent” (from the 18 century) to health reform in the 21st century, other countries are looking forward.

Even as Americans debate whether President Obama’s health-care law and its promise of guaranteed health coverage should be scrapped, many far less affluent nations are moving in the opposite direction — to provide medical insurance to all citizens.

China, after years of underfunding health care, is on track to complete a three-year, $124 billion initiative projected to cover more than 90 percent of the nation’s residents.

Read the article for more examples.

Medicynical Note:  Is it any wonder that other nations sense our social and moral decline. 

We bring new definition to the term leading from the rear.  We are the worst in the world in assuring access to care; we lead the world in costs for health care; we lead the world in health care related bankruptcy.

Medical Debt: America’s the Only One

America’s unique approach to health-care most vividly expresses itself in our health care costs, our lack of universal coverage, and in the medically related debt  (national and individual)  found in our country.  We lead the world!

Even people with good insurance coverage know how hard it can be to figure out how much they owe after a visit to the doctor or, even worse, the emergency room, which can generate multiple bills. But as patients become responsible for a growing share of costs — not just co-payments, but also deductibles and coinsurance — bill paying is becoming ever more complex.

Medicynical Note:  America leads the world in medical debt.  In trying to manage this problem various legislative fixes are “in the works.” (see article above)  Other nations use  preventive medicine and simply, one way or another, provide health-care coverage to all their citizens.  Individual medical debt is unknown. Additionally, because other countries manage their costs, their national bill for health-care (cost of health care/capita) is a fraction of ours.  American exceptionalism at work!!!

Stuff Happens: Young People, Insurability and Cancer

This in the NY Times.  Stuff does happen. 

Legal Lacunae: Generic Manufacturer’s Can’t Be Sued

Interesting advantage to generic drug makers, limited liability for adverse outcomes. 

Dozens of suits against drug companies have been dismissed in federal and state courts because of a decision by the Supreme Court last year that makes it virtually impossible to sue generic manufacturers for failing to provide adequate warning of a prescription drug’s dangers. This outrageous denial of a patient’s right to recover fair damages makes it imperative that Congress or the Food and Drug Administration fashion a remedy.

Medicynical Note:  Its fascinating to view the unintended consequences of what seems a reasonable regulation.  A fix may be in the works but who knows what that will entail and what consequences it will bring.

No doubt our conservative/libertarian friends would argue it would be better to do without regulation and oversight at all.  Really?

Semulaparin: Effective Maybe, Cost Effective?

It’s difficult to assess the cost effectiveness of a new intervention when price data is unavailable.  That’s the case with semulaparin, a new anticoagulant that is not FDA approved.

The NEJM this week reports that using semulaparin decreases the incidence of blood clots in cancer patients.

Venous thromboembolism occurred in 20 of 1608 patients (1.2%) receiving semuloparin, as compared with 55 of 1604 (3.4%) receiving placebo (hazard ratio, 0.36; 95% confidence interval [CI], 0.21 to 0.60; P<0.001), with consistent efficacy among subgroups defined according to the origin and stage of cancer and the baseline risk of venous thromboembolism.

There was a slight increase in bleeding complications in the semulaparin group 2.8% vs 2% in the placebo group.

The authors conclude that the drug reduces the incidence of thromboembolism in patient on chemotherapy.

Sanofi’s press release touted the results as well:

Sanofi (EURONEXT: SAN and NYSE: SNY) announced today results of the pivotal SAVE-ONCO study which demonstrated that, in cancer patients initiating a chemotherapy regimen, investigational semuloparin significantly  reduced the risk of the composite of symptomatic-deep vein thromboembolism (DVT), non-fatal pulmonary embolism (PE) or venous thromboembolism (VTE)-related death by 64%[]i], meeting the study primary endpoint (respectively 1.2% and 3.4% for semuloparin and placebo HR 0.36 95% CI (0.21-0.60)), p< 0.0001).

Medicynical Note:  The daily costs of the currently available low molecular weight heparins are between $35 and $80 dollars/day.  Assuming self-injection and negligible cost for other materials. 

The mean duration of the treatment regimens in the NEJM study was 3.5 months (approximately 100 days).  $35/day for 100 days and 80/day for 100 days gives a treatment cost for patient of between $3500 and $8000/patient.

1608 patients were treated in the study.  Using this number and the estimated cost/day, providing a low weight molecular heparin to these patients would be between $5,628,000 million dollars if the drug costs $35/day and $12,864,000 at $80/day.

The benefit noted in the article was a difference of 35 occurrences of venous thrombo-embolism between the placebo and treated group.  This gives a cost range of between $160,000 and $367,542 per thrombo-embolus prevented.

Cost effective?  Probably not.

Two Ruined Lives: Boy 15 shoots sister

A sad but uniquely American happening

The teen likely killed his sister sometime after 8 a.m., when his parents left to go grocery shopping in Fort Smith, about 40 miles away, Boen said. The boy turned himself in at the sheriff’s department about an hour and a half later.

And:

Guns were confiscated from the family’s home and vehicle, the sheriff said. Authorities were trying to determine which weapon was used in the shooting.

Medicynical Note:  More than two lives ruined.  If you must have guns, please keep them locked up.

Product Line! Bottom Line! The New Paradigm for Medicine—Sleep Apnea

In the past 30 years the diagnosis of sleep apnea has gone from being an oddity to a mainline healthcare business.  Testing and prescribing has become a niche that provides lucrative revenue to specialized businesses.   As noted here:

It’s a condition shown to increase the risk of several serious illnesses, including heart disease, stroke and dementia. Critics, however, worry that overnight tests to diagnose apnea, particularly those done in sleep labs, may be over-prescribed, at great cost to the health care system.

Testing can be a lucrative business, and labs have popped up in free-standing clinics and hospitals across the country. Over the past decade, the number of accredited sleep labs that test for the disorder has quadrupled, according to the American Academy of Sleep Medicine.

At the same time, insurer spending on the procedure has skyrocketed. Medicare payments for sleep testing increased from $62 million in 2001 to $235 million in 2009, according to the Office of the Inspector General.

And:

It’s no secret that the sleep business can be lucrative for physicians. A website for Aviisha, a sleep testing company, has a special page for physicians showing a picture of a doctor with a stack of money in his lab coat pocket. And in February, the American Academy of Sleep Medicine is offering a seminar on the “business of sleep medicine for physicians” at a golf resort in Arizona.

Insurers are catching on and limiting the expensive on site testing encouraging  more use of home testing. 

What’s most interesting about this expenditure is that while there is extensive data showing a short-term improvement in symptoms with treatment there is no long term outcome data documenting effectiveness.  As noted in this presentation by Henry Glick of the University of Pennsylvania from the American Thoracic Society in 2010:

Given the large number of studies, why hasn’t the
question been satisfactorily answered?

  • Shares with health problems such as obesity the fact that while it “makes sense” that treatment should avoid outcomes such as heart attacks and stroke, but no trial has ever demonstrated that treatment actually avoids these outcomes (Medicynical Emphasis)

Medicynical Note:  As noted in a 1999 article on the costs of sleep apnea,

We conclude that patients with undiagnosed sleep apnea had considerably higher medical costs than age and sex matched individuals and that the severity of sleep-disordered breathing was associated with the magnitude of medical costs. Using available data on the prevalence of undiagnosed moderate to severe sleep apnea in middle-aged adults, we estimate that untreated sleep apnea may cause $3.4 billion (probably ten times that amount today) in additional medical costs in the U.S.  Whether medical cost savings occur with treatment of sleep apnea remains to be determined.

Confusing any study of outcomes is the fact that of those treated with CPAP  machines (continues positive pressure) only a minority, perhaps a small minority, continue to use them.

I conclude then, that there is a problem called sleep apnea, caused to a great extent by obesity.   We know, also, that an expensive diagnosis and treatment industry has evolved to manage this problem.  Sleep apnea diagnosis has become a product line for many companies.   There is evidence that  treatments,  some surgical and permanent and others temporary with use of oral appliances and/or machines may (CPAP) improve some symptoms.  But there is no evidence, at this time, that these treatments prevent long term complications (cardiovascular or pulmonary) and death.   For all we know, people treated may have exactly the same outcome as those not treated.

This raising the question of what is a cost effective approach for this problem?  Is our current approach  the most medically effective or do we need to rethink the whole thing?

Health Care Cost’s Moderating? Good News?

The U.S. leads the world in health care spending per-capita.  We spend over 2.5 trillion dollars a year (over 8,000/person) on medical expenses but still have 50 million people lacking health insurance and assured access to care—I don’t count “free” ER access as assured care.  This is one and a half to two times the expenditures of other industrialized countries.

We’ve an approach to health care that’s become unaffordable to most people.  Our country leads the world in bankruptcy due to medical expenses.  To tell the truth such a category is unheard of in other industrialized countries. 

One can cautiously take the recent news that health expenses are “only” increasing at the rate of inflation as progress in gaining control over these expenditures:

Still, the increases for 2010 and 2009 were the lowest measured in 51 years. And health care as a share of the economy leveled off at 17.9 percent, the first time in a decade there’s been no growth.

But:

The main reason for the slowdown was that Americans were more frugal in their use of health care, from postponing elective surgery to using generic drugs and thinking twice about that late-night visit to the emergency room.

Medicynical Note:  After increasing at multiples of inflation for years, health care spending seems to have finally become unaffordable, thanks to increasing  deductibles, co-pays, inadequate coverage  and lack of coverage for over 50 million citizens. 

In these hard economic times we’ve proven that rationing by ability to pay works.  It’s however a blunt instrument.  People lacking resources cut back on care, whether it’s really needed or not.  We may lose a few but then we’re saving money.

Progress?  No.  Rational?  No.

The American Sportsman? Our Rather Sick Gun Culture

In this undated photo provided by the Pierce County Sheriff's Dept., Benjamin Colton Barnes, is shown. Officials said Barnes is a person of interest in the fatal shooting of a park ranger at Mount Rainier National Park, Sunday, Jan. 1, 2012 in Washington State.

It’s alleged that this man shot several people in Washington State this weekend. 

What’s the rationale for these weapons in a civil society? None seem appropriate for hunting; they don’t even seem reasonable, correct me if I’m wrong, for personal security.  Only in America.

Regulation: Save Us from Ourselves

More evidence that children need supervision in the sandbox.  Despite yeoman’s work by Heritage Foundation and the republican party to obfuscate the causes of the financial meltdown—and blame government.  It’s emerging that companies without supervision, when money is involved, do foolish sometimes cynical things.  Take this for example:

Nearly four years ago, we first reported on allegations that Countrywide Financial, the failed lender that was bought by Bank of America after it collapsed, had their system set up so that non-white loan applicants were steered toward subprime loans, even if they could have qualified for a standard mortgage. Well, the wheels of justice turn remarkably slowly in Washington, DC, but today the Justice Dept. finally announced a settlement with BofA for $335 million over these allegations.

Medicynical Note:  The problem was not regulation but rather greed.  And as we’ve noted previously similar issues abound in the medical sphere.  Consider the escalating prices of drugs for people with serious life threatening illnesses; salaries of health related companies executives; the costs of our health care non-system (the highest per capita in the world). 

Sadly, unfettered capitalism opens the door to an empty room.