Category Archives: General Cynicism

No such thing as Cost Effectiveness in U.S. medicine

Medicare has bowed to industry pressure and expanded the use of non FDA approved treatments for cancer. That means very expensive medications with little evidence of effectiveness will be used to treat cancers.

As noted in the article:

“One of the many drugs whose use is likely to expand is the Eli Lilly product Gemzar, which costs $2,500 to $5,000 a month. The F.D.A. has approved it to treat only four types of cancer. But the new rules will virtually guarantee that Medicare will pay for its use for about a dozen other cancers, including advanced cervical cancer – even though the evidence supporting Gemzar for that use is “inconclusive,” according to one of the reference guides Medicare will now be consulting.”

“Under the new rules, Avastin (medicynical note: one of the most expensive medication on the market at $10,000/month) will be routinely covered for ovarian cancer – as will at least some other off-label uses, including for brain and kidney cancer.”

“The new policy, which took effect in November, makes it much easier to get even questionable treatments paid for, critics of the changes say. Medicare is providing “carte blanche in treatment for cancers,” said Steven Findlay, a health policy analyst for Consumers Union. He said overly expansive coverage encourages doctors to use patients as guinea pigs for unproved therapies.”

Medicare has decided that cost effectiveness and value is not a consideration in cancer treatment. Without such analysis any system of health care is a goner.

We need a non-biased organization to review the effectiveness of medications. This evaluation would factor in such issues as whether the drug works for the indication, cost effectiveness and the value to the patient and health care system.

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More Technology, Higher Costs

We have a slavish reliance on technology to get us out of fixes. It’s almost an irrational belief system. We’re counting on technology to fix global warming, inefficient automobiles, to cure diseases and so on. But in our patent-bound world technology may not be the answer to all our problems and may actually costs without changing anything.

President Obama seems to think technology is the answer to our medical non-system’s problems. For example, integrated electronic medical records are a technological tour de force. They improve communication between physicians and marginally makes life easier in the paperless physician’s office, but do they improve patient care? That remains to be seen. The cost of the new technology, however, is tremendous both for the initial installation and the yearly maintenance. Guess who gets to pay? Savings, I doubt it.

Scientific American has doubts as well and cites this article in Health Affairs by Lawrence Baker. The abstract notes;

“As anticipated by previous research, increases in the supply of technology tend to be related to higher utilization and spending on the service in question. In some cases, notably diagnostic imaging, increases in availability appear associated with incremental utilization rather than substitution for other services.”

Consider PET scan technology. This diagnostic test does add to our information for certain cancers at a cost of $5000/test. Previously a patient had a CAT scan and/or MRI to image the tumor. With the advent of the PET, we now, in many instances, do all three. Figuring about $1000 for the CAT scan, an average of $2000 for an MRI and $4000-$6000 for an MRI, the cost of imaging alone today exceeds what it cost for the entire treatment, including surgery, 25 years ago. It’s debatable whether patient outcomes (survival) are better but what is not debatable is that costs are higher. We need better guidelines for use of these procedures.

The same can be said for other technology in the medical field, including new drugs. Their use may not improve outcomes but they will increase costs. This has to change.

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The Corporate University, an extension of corporate research–Good? Doubtful

I haven’t read the book, “The Last Professors: The Corporate University and the Fate of the University”, but this discussion of the goals of education seem relevant to our system of medical education. I’ll be getting it soon. This, from a review in the NY Times:

“There is an important difference between learning which is concerned with the degree of understanding necessary to practice a skill, and learning which is expressly focused upon an enterprise of understanding and explaining.”

Forty years ago medical professors were engaged in education and research. Their educational goal was to train physicians and medical researchers. Their research goal was to understand and explain medical issues. At the time relationships between researchers and the medical industrial complex were discouraged and frowned upon. One had the sense that such relationships were unethical and broke down objectivity in research. Money from the companies was somehow tainted.

Guess what they were right. Today our system runs on conflicts of interest. Universities and their staffs seem more concerned with outside activities. obtaining lucrative patents, and business relationships than teaching. They are no longer institutions of “higher” learning, rather they are institutions of higher income.

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Corrupt Industry Practices– Lilly pays 1.42 Billion in fines

Drug companies spend more on marketing drugs than they do on research. Lilly is pleading guilty to illegally promoting it’s anti-psychotic agent Zyprexa for other uses.

“Lilly admits it promoted Zyprexa in elderly people to treat dementia, a use not approved by “the Food and Drug Administration,

“Zyprexa, used to treat schizophrenia and bipolar disorder, had sales of $4.76 billion in 2007, accounting for about a quarter of Lilly’s revenue. The drug, part of a class of medications called atypical antipsychotics, has been linked to excessive weight gain and diabetes.” \

This is not the first settlement for Lilly regarding this drug. It has also paid over a billion dollars to patients for harm caused by inappropriate use of this drug.

“The fine would be in addition to $1.2 billion that Lilly has already paid to settle 30,000 lawsuits from people who claim that Zyprexa caused them to develop diabetes or other diseases. Zyprexa can cause severe weight gain in many patients and has been linked to diabetes by the American Diabetes Association.”

“Internal Lilly marketing documents and e-mail messages showed that Lilly wanted to persuade doctors to prescribe Zyprexa for patients with age-related dementia or relatively mild bipolar disorder.”

Earlier Lilly had a marketing scheme to doctors “Viva Zyprexa” (sound familiar?) aimed at urging the sue of the drug in dementia.

“In one document, an unidentified Lilly marketing executive wrote that primary care doctors “do treat dementia” but leave schizophrenia and bipolar disorder to psychiatrists. As a result, sales representatives should discuss dementia with primary care doctors”

Zyprexa costs in the range of $4000-$6000/year or more depending on the dose.

Medicynical note: Corrupt insurer (see yesterday’s post on Unitedhealth) and pharmaceutical company practices go away with a national health care program. In that new world which is reality in other industrialized nations, health insurance, drug utilization and pricing would be more carefully reviewed and supervised.

One wonders what happened to the “ethical” pharmaceutical industry, as it was called in the 60’s?

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Unitedhealth–Scamming doctors, scamming patients, the American Health care system

United Health has agreed to pay 50 million dollars

“Ending a practice doctors say underpaid them and led to higher costs for patients, UnitedHealth Group Inc. on Tuesday agreed to pay $50 million to establish a new database that will be used to determine rates for patients who choose physicians outside the insurance giant’s network.”

But of course while paying the money Unitedhealth denied wrong doing.

What’s remarkable about this is that other insurers use this database and also have underpaid for services, so the problem is broader than Unitedhealth:

“But because other health plans, such as Blue Cross and Blue Shield of Illinois, use the Ingenix database to determine their rates for out-of-network care, the impact is much broader”

Medicynical note; Unitedhealth and other insurers have single-mined devotion to making money. Whether that requires scamming doctors as above, scamming patients, or increasing Unitedhealth executive salaries,

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Samuelson’s solution to Healthcare– Increase taxes

It’s fascinating to watch the health care debate develop. This today in the Post:

“We could charge the elderly more for Medicare. We could tax employer-provided health insurance as ordinary income. We could create a dedicated federal tax to cover government health costs — if health spending increased more than revenue, the tax would automatically rise. People would quickly feel the costs of our present system. Of course, that would be unpopular, because it would compel Americans to face a discomforting issue — how important is health care compared with other priorities?”

Medicynical note: Mr. Samuelson seems to think we need to increase the costs to people by increasing taxes on health care. His proposal, however, will increase those who cannot afford health care much less more expensive insurance. He believes this will decrease use of the health care system and decrease costs. A little like the “let them eat cake” solution.

Free market approaches in health care simply don’t work. Patients are not in a position to comparison shop and cannot be fully aware of cost implications and all the options. Health insurance, for example, has been a “free market” for years and failed to providing affordable comprehensive care. Insurers are more concerned with their bottom line than quality care.

As noted by the McKinsey study, health care has become unaffordable. Insurance is overpriced; cost effectiveness is not a consideration; and utilization in some areas is excessive. Overpricing, as advocated by Samuelson, increases the uninsured, the tendency to delay preventive medical services and the use of expensive inefficient emergency rooms. His solution is more of the same and does nothing to decrease inefficiency and waste in the system.

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PacifiCare (UnitedHealth) Fined for Denying Claims without reason

In Oregon, PacifiCare, a division of United Health, has been fined for denying claims without investigating whether the patient’s problem was covered by their policy.

“The consumer and business services’ insurance division found that PacifiCare Life Assurance had refused to pay for claims without first contacting enrollees or their health-care providers, Martinis said.”

“State officials also determined that PacifiCare failed to act promptly on claims and made enrollees with pre-existing medical conditions wait one year for coverage. Oregon law requires insurance companies to cover pre-existing conditions after a person has been enrolled in a health plan for six months.”

“As a result of the state’s investigation, PacifiCare Life Assurance performed an internal review and paid nearly 5,000 claims that it previously denied without first conducting an investigation.”

“The insurer also took corrective action and paid more than 2,000 claims to which it had applied a 12-month pre-existing conditions provision.”

Medicynical Note: This company insures only 13,000 people in Oregon. They apparently denied 7,000 claims from this small population. Does anyone believe that these practices are limited? Are limited only to Oregon? Only to this division of UnitedHealth?

Private insurers are not there to provide coverage for or access to quality health care, they are in it for the money. The sooner we understand that the fiduciary responsibility of these companies is not to do good, the sooner we will be able to have a better, more responsive, possibly less expensive health care system.

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Market Based Health Care, Patent Reform

George Will and Mike Leavitt think buying health care should be like buying a car:

“Leavitt says that until health care recipients of common procedures can get, up front, prices they can understand and compare, there will be little accountability or discipline in the system: “In the auto industry, if the steering-wheel maker charges an exorbitant price, the car company finds a more competitive supplier. In health care, if the medical equipment supplier charges an exorbitant price, none of the other medical participants care.””

Price should be part of the health care equation. The cost of everything should be up front and open to scrutiny. Insurers should bargain for the best deal for their customers. These negotiated prices should be common knowledge so that all needing health care can benefit.

What’s missing from Mr. Will’s analysis is an understanding that patients are not in a position to shop health care. Finding the “best price” for emergency care and most other health care needs is simply not possible and the patient has to take whatever is available from the local supplier at the demanded price. Furthermore, health care is not like other commodities that people can take or leave as they wish. Buying a car or even a new home is an optional expenditure, health care is not. Yet health care costs/year for an individual can now approach and exceed these large expenditures.

Patient’s health care decisions reflect their anxiety, personal bias, financial status and understanding of the situation. This last factor should not be underestimated. Patients in the majority of instances cannot fully understand the risks and/or benefits of treatments and the alternatives, much less concern themselves with cost efficiency data. He/she is thus greatly influenced by physicians, manufacturers, insurers, etc. all with superior knowledge of the situation. All these advisors have extreme conflicts of interest that interfere with unbiased advice and undermine the notion of a “free health care market”–it doesn’t exist.

Our health care market doesn’t encourage efficiency, but rather it promotes over utilization. Providers and suppliers make more when there is consumption of health care services and products. One only has to experience inaccurate and highly deceptive TV ads for pharmaceuticals and procedures to understand that consumption is the name of the game, not cost efficiency.

The failure of free market forces in health care is graphically demonstrated in the insurance market. Insurers, in the U.S., spend an estimated 30% of revenue on administrative costs while other industrialized countries manage with between 7 and 15% for administrative costs–that’s over 100 billion dollars wasted. Our expenditures/capita are similarly elevated. Even with these excess expenditures, 50 million of our citizens are uninsured. CEO’s of insurance companies understand they are in business to make money and not deliver and/or pay for quality economical care. Much less provide health care for all.

There is even worse inefficiency in the pharmaceutical industry where products are given generation long monopolies (patents) that eliminate price competition. Companies price drugs based on the severity of the condition rather than their costs of development. They figure more seriously ill people can be coerced into paying more. They have been correct thus far. In the U.S. free markets are interpreted to mean free to make maximum profit.

Ewe Reinhard correctly believes part of the problem is the inefficiency of physicians and their inherent conflict of interest. He proposes a very complex system to control payments to physicians and encourage the right pricing and monitoring of utilization of health care resources.

“Studies have shown that physicians are not impervious to the financial incentives inherent in fee-for-service payments. For example, on average, physicians who have a direct financial interest in the use of imaging services, like CAT scans or M.R.I. scans, recommend far more such services for their patients than do physicians without such financial interest.”

He also notes that:

“there is now a worldwide movement to replace the system with so-called “evidence-based case reimbursement”. Under this approach, one single payment would cover all of the supplies and services that are needed, under best, evidence-based clinical practices, to respond adequately to well-defined medical conditions.”

and:

“For example, it is technically feasible to capture electronically every supply and service requisitioned by every doctor in a hospital for every patient, by type of supply or service ordered. It is also feasible to electronically capture detailed information on the health status of every patient admitted to a hospital.”

With due respect for Dr. Reinhardt, such a system seems likely to have unintended consequences because of it’s complexity. We are violating the KISS principle (Keep it Simple Stupid).

Paying a fixed amount per diagnosis seems simple and unbureaucratic. But it sounds suspiciously like the the DRG payment system currently used by Medicare other insurers. That system is an administrative nightmare that underpays providers and forces them to maximize diagnoses to increase reimbursement. Often providers decide that they cannot afford to provide care for the payment offered and increasingly are refusing patients covered by this limited rigid reimbursement system.

Similarly, scrutinizing every expenditure seems unreasonable and not really possible.

An additional problem with reimbursements is that the system as it is currently organized rewards proceduralists and doesn’t pay enough for patient contact time and intellectual effort. Most physicians have large debt from medical education; their office overhead and data collection requirements all cost big bucks; billing is complex as physicians are forced to justify their approach to each patient problems. As a result the underpaid primary care specialists are literally disappearing. This doesn’t change in Reinhardt’s proposed reimbursement system, and may actually worsen with the added billing oversight.

Health care expenditures will continue to rise as long as pharmaceutical and technology companies have patent protection for a generation and are not scrutinized for excessive pricing. These players are literally sucking the system dry.

I would favor providing support for medical education in return for some quid pro quo, whether several years working on salary or participation in government health care programs or a commitment to accept the fees offered by government sponsored programs. I certainly agree we must include methods of scrutinizing health care expenditures but also think the primary emphasis should be to provide incentives that promote careful cost-effective primary care, with appropriate use of new advances, while maintaining productivity.

Patent reform must also be part of the mix and I would suggest a market based reform. New technology’s pricing would be scrutinized by a board during the patent process. The product or procedure would be compared others. Companies pricing their new product or procedure reasonably would be rewarded with a patent for the full time period. Companies pricing their “advances” excessively,(based on efficacy, costs of development and comparable product cost) would still get patents but they would be for a proportionall
y shorter period of time –proportional to the excess pricing of their product. Price increases once the product is marketed would be limited to the cost of living or else the patent length would be reduced.

The greatest challenge is lining up incentives in the system to reward cost effective high quality medical care.

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Paying for Healthcare: who pays the costs of the uninsured

Our non-system of health care has institutionalized the most inefficient, most costly and least effective way of paying for and delivering health care. The problem is most extreme for those who are indigent and/or have no health insurance coverage. They/we pay more for lousy health care. No wonder our health care outcomes are so mediocre.

People who are uninsured and have no access to health care are forced to delay care. Minor problems become major and costs for care, when sought, are higher. Guess who pays these higher costs when the uninsured can’t pay their bills?

When the uninsured and/or indigent become sick their problems are handled inefficiently (at ER’s for example) and other higher cost facilities. Guess who gets to pay for these excess costs when the uninsured are unable to pay?

If an uninsured person is fully indigent he/she may qualify for Medicaid. Guess whose taxes pay for this insurance?

Finally, w hen an uninsured person shows up at a hospital or other facility he/she pays retail. That is, their charges do not reflect the discount that insurers and industry insiders negotiate. So those least able to pay end up paying the most. That’s the reason one of the leading causes of bankruptcy in the U.S. is medical bills. Guess who pays for these unpaid bills with increased charges for their own services?

All of this goes away with universal coverage in a national insurance program. We need that change, now!

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Abstinence education, Virginity Pledges –Failed concepts both here and in Africa

In of all places, Bloomberg, there is an article on the failure of abstinence education and “virginity pledges, more here. These faith based approaches to teen pregnancy and controlling the HIV/AIDS epidemic rely on “reason” to control lust. Unfortunately several studies have now shown that this approach doesn’t work. In the U.S. young people taking virginity pledges were as likely to have sex as those not doing so. Imagine how effective this approach is in Africa controlling HIV/AIDS.

The article reported:

“Teenagers who pledged to avoid sex until marriage were as likely to have intercourse as other U.S. adolescents, according to a survey of conduct mostly in 1990s.”

“Teens who took the pledge also were less likely to use birth control pills or condoms”

“Today’s study relied on surveys of students in 1996, when Congress authorized increased funding for abstinence-only education as part of an overhaul of welfare, and 2001. A Congressionally authorized report in 2007 on the program in that bill, Title V, also found students were no more likely to abstain. That program gets about $50 million a year.”

The article notes a study showing some effectiveness in one program but the overall results indicates that the strategy is not a success.

And from Freakonomics:

“Studies have repeatedly shown that abstinence-only students have almost the same number of sexual partners, and have sex almost as early, as students who receive traditional sex ed. In fact, abstinence-only programs may actually increase the risk of STDs and unintentional teen pregnancies. That’s because those abstinence-only students who do have sex tend to be less likely to use protection.”

What’s fascinating about the discussion in the article is the all or none philosophy of the abstinence types. They simply won’t countenance a program that has both abstinence and safe sex components. It’s another example of pre-existing bias affecting the implementation of public policy.

Young people need all the information and advice available. We need to encourage abstinence but also equip them to protect themselves when and if they decide to be sexually active. People are not machines with on off switches, they need options and alternatives.

Meanwhile in Africa the AIDS epidemic continues and the U.S. policy to deemphasize safe sex and emphasize abstinence , more here, does not appear to promoting abstinence. Those counseled were more likely to use condoms, abstinence doesn’t appear to be likely in those situation. The study in Nigeria “did not see a reduction in the number of partners.”

So in Africa we have a program forced to devote 1/3 of it’s spending on an ineffective strategy. Inefficiency in our health care programs is not limited to our domestic health care system.

Medicynical comment: What’s fascinating is that when one does a google search on abstinence education Africa, you find many sites associated with church causes promoting the concept but relatively few facts. We need more studies on this and need to merge the two approaches–abstinence and safe sex.

For the record most of these Christian groups, including Rick Warren’s, had nothing to do with HIV for the first twenty years of the epidemic. That neocon icon, Ronald Reagan, couldn’t even bring himself to say the word AIDS during his presidency. Twenty million people died and another twenty or so million became infected in this period.

These groups opposed funding of any anti-HIV intervention in the 80’s and 90’s. Their philosophy, as voiced to me by a missionary in Uganda in 1988, was that those with HIV got what they deserved. When Bush, to his credit, decided to put money into HIV in Africa. These churches, so to speak got religion, and followed the money. The only problem is that they wish to dominate the program with an ineffective HIV education message. Hopefully this will change.

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