It’s fascinating, these drugs have been around for about 15 years. They were never thought to improve disease survival and were marketed aggressively directly to consumers as well as physicians as medications that help people cope with their treatment. (“Ask your doctor about ………”) Now we find “they can increase the risk of death and tumor growth.”
The companies involved have made billions of dollars on these medications, they were expensive and given on a regular basis throughout the treatment cycle. It’s hard to believe that no one along the way seriously considered the possibility that the drugs might worsen prognosis–I know it was a consideration in hematologic malignancy.
In other countries their use was limited because of their cost and because the countries negotiated their prices were lower.
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