Progress–Remdesivir

In the trial, patients who received remdesivir recovered 31% faster than those who received a placebo, a finding of superiority that could not be attributed to chance, researchers reported. Specifically, half of the patients who were randomly selected to be treated with remdesivir were considered completely recovered within 11 days, and half of those patients took longer. By comparison, it took 15 days or less for half of those who received the placebo to recover.”

“The results also suggested that patients who were given remdesivir were more likely to survive COVID-19 than were those who got the placebo. But the difference in fatality rates — 8% for the group that took the drug versus 11.6% for the placebo group — fell slightly below the cutoff point at which researchers could rule out a statistical fluke.”

Medicynical note: some good but not great news. Remdesivir has activity against the civic-19 virus but the activity is marginal. Comparison of fatalities in the study between those receiving the drug and those getting placebo were not quite statistically significant. The decrease in recovery time was significant. 11 days to recovery vs 15 is progress but not what I would hope to be the ultimate solution.

Use of this drug earlier in the course of the disease may provide more profound benefit. As Dr. Fauci implies this is a start towards an effective treatment.

It should be pointed out that when a very active medication is found it will not take large studies to prove its worth. Remdesivir is a good first step.

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